Vanilla is the second most expensive spice following saffron. Vanilla remains pricey (around $3.50 a pod) largely due to the fact that it is very labor-intensive and challenging to grow. Originally from Mexico, the vanilla orchards had a highly symbiotic relationship with its natural pollinator, the Mellipona bee. Man-made attempts to replicate what nature was doing best by artificially pollinating the plant were largely unsuccessful until the discovery that the vanilla plant could be hand pollinated, thus enabling the plant to be grown in areas outside of Mexico.